The Bills roll into this divisional bout ranked second in the NFL in total offense (415.9), third in passing offense (279.2), and second in points per game (28.1). Anyone who has followed it is way up.īuffalo owns a potent and electric offense that can score plenty of points. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. The model enters Week 13 of the 2022 NFL season on an incredible 155-110 run on top-rated NFL picks that dates back to the 2017 season. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. Bills picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. Patriots odds from Caesars Sportsbook, and the over/under is 44. Buffalo is favored by four points in the latest Bills vs. Thursday's game will be the first meeting between the teams since Buffalo routed New England, 47-17, in last season's Wild Card round. Meanwhile, the Patriots (6-5) are fourth in total defense (307.8 yards per game). The Bills (8-3) rank second in the league in total offense (415.9 yards per game). One of the NFL's best offenses will face one of the league's best defenses when the Buffalo Bills visit the New England Patriots in a key Week 13 Thursday Night Football game at Gillette Stadium.